All depends on the give back on the machine and what is required.. Truth is big name casinos generally pay back better (Freemont actually has some machines that are potentially +ev with a reported 98-99% payback meaning its not hard to come out ahead potentially). I generally avoid Indian Casino slots because their payback is usually shitty.. The exception is if Im killing time before a poker tournament and decide to trop $20 in a machine to try and get a little lucky by chance..