The odds bet has no advantage to the house, (the house advantage is on the line) so in your lifetime it shouldn't matter how you play it.

However you have to have a bankroll to sustain it and few have the bankroll for 100x odds. You hit a bad set of rolls and bust out and the casino wins your money before you can get to the good rolls.

Personally I only play double odds, it is all I can afford. Doesn't matter if the table is 3,4,5 or 100x.

I guess that is how the take for a craps table can be 14-20% when the basic bets are 1.5% advantage. I guess prop bets help the casino there.