There's nothing like erudite gamblers who conflate flipping coins with predicting behaviors between organisms. God bless them, every one, you know, like Tiny Tim.
The technical response would be something like, "for sports gambling, mathematical analysis is helpful from an odds perspective but not sufficient and not even necessary to make a profit." Whereas knowing the organisms involved, while technically not sufficient (in case you're laying ridiculous odds) is necessary.
For example, I bring up the example of the Kentucky team doctor betting Indiana in LV prior to the Kentucky/Indiana game. No amount of mathematical analysis is going to do much to move the needle on which team one should bet.
Trying to assign "EV" to such events is absurd and is frankly the height of arrogance.





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